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Off Key - General Discussion

A place to talk about whatever you want

2.4k Topics 17.5k Posts
  • Oops

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  • Ozempic

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    wtgW
    But, after getting a CT-scan and seeing a neuro-ophthalmologist, it was revealed he had non-arteritic anterior ischemic optic neuropathy (NAION), a condition in which the loss of blood flow to the optic nerve causes sudden vision loss. Recent studies have shown an association between drugs such as Ozempic, Mounjaro and Wegovy — which have become phenomenally popular for weight loss — and an increased risk of NAION [. Of the estimated 15 million Americans now taking such medications for Type 2 diabetes and weight loss, only a relative few have experienced the issue, but for those who have, it’s life-altering. https://nypost.com/2025/03/08/health/people-going-blind-after-using-weight-loss-drugs-like-ozempic-and-mounjaro/ From my eye researcher friend: Another thing associated with these drugs is cataract formation. I have a 30-something patient recently who was having trouble seeing at night, not because she couldn't see under low levels of iullumination, but because lit signs were blurry and headlights dazzled her. This began a year after starting tirzepatide. She also had naturally very large pupils. No one thought to look at her lens because she was so young. The public is doing a clinical trial on themselves. I'm so glad I haven't had to fight obesity.
  • A conversation with Fiona Hill

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  • We are in a TV show?!?

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    C
    When the reality sink in? Will it matter?
  • Making China Great

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    A
    Interesting video. If only their government was nicer.
  • Faraday’s notebooks

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  • US Institute of Peace

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    S
    I wonder when the Doggy children will hit the DOT. Can’t wait for bridges to fall in to rivers.
  • When did we develop the capacity for language?

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  • Caregiver app Tendercare

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  • Louise Penny's new book

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    RontunerR
    Predicting the future!
  • Buyer’s remorse

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    Leopards, faces, etc.
  • Question for SK

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    Thanks!
  • Schumer finally speaks up

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    @Bernard "But already Trump is ignoring the courts. He is deporting people despite the court order halting the deportations. " So he is in contempt of court. It's possible this will make a difference, that it is contempt, rather than that he had the legal right to do it and so is untouchable. I've also pretty much lost all faith in the Ds. There is going to have to be some kind of organic uprising. No one is going to save us but ourselves.
  • Gorbachev & Trump(CF)

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    I can't watch her because any freeze frame of her face is a contorted smirk making watching a video of her an exercise in torture.
  • Deported

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  • Fun video. (There’s a piano)

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    ShiroKuroS
    @Jodi that was great!
  • Tesla problems

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    I’m not sure it matters anymore. The market for electric cars is way different from the market for Swasticars and Wankpanzers. Let it burn.
  • Let’s all thank god Elizabeth Warren failed

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    Yes, let's not allow anything that might interfere with unfettered capitalism. That POV is what got us into this mess.
  • Hey Horse Peeps

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    what jodi said.
  • The Social Security program

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    The overhaul needed previously (Reagan/ Monyhan) and I believe all previous major overhauls before that, went through the entire legislative process of relevant committees, etc. Social Security was changed, "saved," and we have a surplus as of today. It worries me that Congress today doesn't seem very interested in doing its job of legislating.