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  4. Be careful with weight loss drugs

Be careful with weight loss drugs

Scheduled Pinned Locked Moved Off Key - General Discussion
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  • B
    B
    Bernard
    wrote last edited by Bernard
    #1

    Yikes.

    Lawsuits are piling up against major GLP-1 makers Eli Lilly and Novo Nordisk as more patients accuse popular drugs like Ozempic and Zepbound of permanently damaging their eyesight.

    Are GLP-1s causing blindness?

    The industrial revolution cheapened everything.

    1 Reply Last reply
    • ShiroKuroS
      ShiroKuroS
      ShiroKuro
      wrote last edited by
      #2

      OMG!

      a 63-year-old man was prescribed Ozempic to manage his diabetes in 2023 and woke up four months later with loss of vision in one eye. He continued taking the medication, not knowing it had been linked to vision problems in some clinical trials and studies, and lost sight in his other eye in October 2024.

      "Now legally blind, Engel has had to quit his job and give up his commercial driver’s license. He can’t see his grandkids play baseball, he said, and the couple has shelved much of their retirement travel bucket list," USA TODAY reported.

      Ok, also this:

      There is currently not enough research to definitively establish a cause-and-effect relationship between GLP-1s and NAION or other vision changes.

      But seriously, these glp-1 drugs are so new, doctors should be more cautious about prescribing them, and any new illness or symptom in a person on a glp-1 maybe should lead to increased scrutiny of possible connections.

      J 1 Reply Last reply
      • ShiroKuroS
        ShiroKuroS
        ShiroKuro
        wrote last edited by
        #3

        P.S. i meant to say, "not enough research to definitively establish a cause-and-effect relationship" does not mean that such a relationship doesn't exist.

        1 Reply Last reply
        • ShiroKuroS ShiroKuro

          OMG!

          a 63-year-old man was prescribed Ozempic to manage his diabetes in 2023 and woke up four months later with loss of vision in one eye. He continued taking the medication, not knowing it had been linked to vision problems in some clinical trials and studies, and lost sight in his other eye in October 2024.

          "Now legally blind, Engel has had to quit his job and give up his commercial driver’s license. He can’t see his grandkids play baseball, he said, and the couple has shelved much of their retirement travel bucket list," USA TODAY reported.

          Ok, also this:

          There is currently not enough research to definitively establish a cause-and-effect relationship between GLP-1s and NAION or other vision changes.

          But seriously, these glp-1 drugs are so new, doctors should be more cautious about prescribing them, and any new illness or symptom in a person on a glp-1 maybe should lead to increased scrutiny of possible connections.

          J
          J
          jon-nyc
          wrote last edited by
          #4

          @ShiroKuro said:

          But seriously, these glp-1 drugs are so new, doctors should be more cautious about prescribing them, and any new illness or symptom in a person on a glp-1 maybe should lead to increased scrutiny of possible connections.

          They’re over 20 years old. It’s just that prescribing them for weight loss is newish. Used to be just diabetes.

          1 Reply Last reply
          • J
            J
            jon-nyc
            wrote last edited by jon-nyc
            #5

            I strongly suspect that the risk to your health of obesity greatly exceeds the risk of this potential side effect if it is one.

            I’m probably more attuned to thinking about relative risks with medications given that I take drugs known to cause chronic kidney disease (with utter certainty, the only question is severity) and increase my skin cancer risk by 100x (not a typo). My alternative would be to die in a couple of months as my body rejects my lungs.

            1 Reply Last reply

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