Q: What's worse than glyphosate?
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A: Its replacement, diquat.
https://www.theguardian.com/environment/2025/jul/06/weedkiller-diquat-organ-damage-study
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Only time I used it was for poison ivy and Japanese knotweed. For the latter I cut it to ground level and paint the stuff on the cut edge with a small paintbrush.
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I've used Roundup to eradicate Bermuda grass lawns and convert to desert/native plants. I wouldn't touch it now.
The alternative is to cover the lawn in black plastic in the summer (April through September in Arizona!) and basically kill it by drought and heat.
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You can use cardboard too, at least here you can