Ozempic
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My guess would be that many stop because of the cost. Others stop because of side effects, some of which appear to be avoidable and others that don’t.
I also think at least some stop because they get tired of not being able to eat the way they like to eat.
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A web search lists the same reasons I did above and one more. Some people lose weight like crazy on GLP and others lose more slowly. There are generally plateaus. People who lose more slowly can get frustrated and give up.
The people who lose weight most quickly appear to be people who have a lot to lose and people with poor diets when they start. Interesting that these same people are also the ones who do well on IF routines.
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But, after getting a CT-scan and seeing a neuro-ophthalmologist, it was revealed he had non-arteritic anterior ischemic optic neuropathy (NAION), a condition in which the loss of blood flow to the optic nerve causes sudden vision loss.
Recent studies have shown an association between drugs such as Ozempic, Mounjaro and Wegovy — which have become phenomenally popular for weight loss — and an increased risk of NAION [.
Of the estimated 15 million Americans now taking such medications for Type 2 diabetes and weight loss, only a relative few have experienced the issue, but for those who have, it’s life-altering.
From my eye researcher friend:
Another thing associated with these drugs is cataract formation. I have a 30-something patient recently who was having trouble seeing at night, not because she couldn't see under low levels of iullumination, but because lit signs were blurry and headlights dazzled her. This began a year after starting tirzepatide. She also had naturally very large pupils.
No one thought to look at her lens because she was so young.
The public is doing a clinical trial on themselves. I'm so glad I haven't had to fight obesity.