Ozempic
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My guess would be that many stop because of the cost. Others stop because of side effects, some of which appear to be avoidable and others that don’t.
I also think at least some stop because they get tired of not being able to eat the way they like to eat.
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A web search lists the same reasons I did above and one more. Some people lose weight like crazy on GLP and others lose more slowly. There are generally plateaus. People who lose more slowly can get frustrated and give up.
The people who lose weight most quickly appear to be people who have a lot to lose and people with poor diets when they start. Interesting that these same people are also the ones who do well on IF routines.